开发新的生物监测技术、离体和活体生物毒性测试和生物标记物方法、以及分子毒理学研究手段,探讨水中有毒污染物的生态毒理;通过地表水、饮用水、再生水、以及污水和废水不同深度处理工艺效果评价等具体案例研究,发展水质安全性评价、水生态风险和健康风险评价的方法和理论。
研究方向
组 长 | ||
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马 梅 | 研究员 |
成 员 | ||
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王子健 | 研究员 | |
许宜平 | 副研究员 | |
饶凯锋 | 助理研究员 | |
马金锋 | 助理研究员 | |
李娜 | 助理研究员 | |
韩颖楠 | 助理研究员 |
博士生 | ||||
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李春梅 | 黄泽昊 | 陈睿 | 韩颖楠 | 徐雄 |
侯瑞 | 黄超 | 闫赛红 | 洪响声 | 高小中 |
袁圣武 |
硕士生 | ||||
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许美佳 | 季晓亚 | 李强 | 梁梦梦 |
1. 国家自然科学重大基金项目(51290283):水质复合污染的毒理效应及风险因子识别, 2013-2017,王子健,课题负责人;
2. 国家自然科学基金重点项目(21437006):水环境中有机磷阻燃剂的环境暴露、生态风险和毒理机制,2015-2019,王子健,项目负责人;
3. 国家自然科学基金项目(20207011):腐殖酸和胶体对疏水有机污染物两相分配和生物吸收影响2003.1-2005.12,马梅,课题负责人
4. 国家自然科学基金项目(50378089):饮用水生产过程中微量有机污染物及其毒性变化规律,2004.1-2006.12,马梅,课题负责人
5. 北京市自然科学基金项目(8052018):北京市不同水体中环境内分泌干扰物分布及生物效应研究,2005.1-2008.1,马梅,课题负责人
6. 北京市科技计划重大项目课题(D0605004040221),自来水水质安全评价指标方法与突发事故的水质保障技术及应用2006.1-2007.12,马梅,课题负责人
7. 国家高技术研究发展计划(863探索导向项目,2007AA06Z414):核受体超家族检测化学品和环境样品内分泌干扰物效应的新技术2007.8-2010.8,马梅,课题负责人
8. 国家自然科学基金项目(50778170):水处理工艺过程中环境内分泌干扰物的变化规律2008.1-2010.12,马梅,课题负责人
9. 中国科学院知识创新工程重要方向项目群项目( KZCX2-YW-Q02-05):有毒污染物的分子毒理和筛选技术2009-2011,马梅,课题负责人
10. 国家高技术研究发展计划(863计划重大项目2012AA06A302):化学品毒性高通量生物测试与评价技术2012.1-2015.6,马梅,课题负责人
11. 中国科学院前沿科学重点研究项目(QYZDY-SSW-DQC004):饮用水复合污染风险因子识别与控制原理,2017-2021,马梅,课题负责人;
12. 国家自然基金面上项目:长期低剂量二苯酮对鱼类毒性与毒理机制研究,2017-2020,查金苗,课题负责人;
13. 国家自然基金面上项目(21677155):卤代多环芳烃在饮用水消毒过程中的形成机制研究,2017-2020,王东红,课题负责人;
14. 环境保护部《跨界江河生态环境安全评估与监控管理》项目课题:流域水环境中高风险有毒有害物质筛选研究,2016-2016,王东红,课题负责人;
15. 环境保护部《重点流域环境保护监管》项目课题:重点流域风险污染物筛选,2015-2015,王东红,课题负责人;
16. 环境保护部《水污染防治》项目课题:典型流域水环境风险污染物筛选与分析研究,2014-2015,王东红,课题负责人;
17. 国家自然基金面上项目(20977102):环境酚类污染物识别和确认方法的研究,2009-2012,王东红,课题负责人;
18. 国家自然基金面上项目(50878205):饮用水中潜在风险污染物的筛查和健康风险评估,2008-2011,王东红,课题负责人;
19. 国家高技术研究发展计划(863计划)重点项目(2008AA062501):环境污染的健康风险评价和控制关键技术/饮用水消毒过程健康风险控制技术,2008-2012,王东红,课题负责人
20. “十一五”国家科技支撑计划重点项目(2007BAC27B02): POPs风险识别与评价技术示范,2008-2011,王东红,课题负责人;
21. 国家自然基金面上项目:区域特征与摄食模式对沉积物中化学物质的生物累积性与生态效应的影响,2016–2019,许宜平,课题负责人;
22. 国家自然基金青年基金:生物模拟采样技术用于沉积物中有机污染物的生态效应评价,2009–2011,许宜平,课题负责人;
23. 国家973计划研究专题:新POPs对鱼类甲状腺激素干扰作用机制,2009–2013,许宜平,课题负责人;
24. 环保公益项目:水生态基准框架与典型案例预研究,2010–2012,许宜平,课题负责人;
25. 863课题:水质安全生物预警监测技术与系统,2014年1月-2017年12月,饶凯锋,课题负责人;
26. 中国科学院科技服务网络计划(STS计划)项目:基于水生生物综合毒性的水源地水质在线连续监测设备的研发和应用,2016-2017,饶凯锋,课题负责人;
27. 国家自然科学青年基金:基于水生态毒理过程的环境风险评价模型研究,马金锋,课题负责人;
28. 国家863重大环境污染风险场预警技术项目,马金锋,课题负责人;
29. 国家863重大环境污染处理处置技术工具包项目,马金锋,课题负责人;
30. 国家863基于物联网的城市水处理系统研究及应用,马金锋,课题负责人;
31. 水专项城市供水应急预案研究与示范课题,马金锋,课题负责人;
32. 水专项南水北调中线水源区特色矿产重金属污染全过程控制关键技术研究与示范,马金锋,课题负责人;
33. 国家自然科学基金青年基金:异源二聚体介导的II型核受体环境内分泌干扰作用机理研究, 2012-2014,杨明嘉,主持;
1. Ma, M.; Zhu, W.; Wang, Z.J.; Witkamp, G.J. Accumulation, Assimilation and Growth Inhibition of Cu on Freshwater Alga (Scenedesmus subspicatus 86.81 SAG) in the Presence of EDTA and fulvic acid. Aquat. Toxicol., 2003, 63: 221-228.
2. Ma, M.; Rao, K.F.; Wang, Z.J. Mutagenicity of Water and Sediment Extracts from the Yongdinghe Watershed. J. Environ. Sci. & Health, Part A, 2003, 38(9): 1781-1791.
3. Ma, M.; Wang,C.X.; Wang, Z.J. Assessing taoxicities of hydrophobic organic pollutants in Huaihe river by using two types of sampling. J. Environ. Sci. & Health, Part A, 2005, 40(1): 331-342.
4. Ma, M. Li, J.; Wang, Z.J. Assesing the Detoxication Efficiencies of Advanced Tretment Technologies for Secondary Sewage Effluents by using a Battery of Biomakers. Arch. Environ. Contam. Toxicol., 2005, 49: 480–487.
5. Ma, M.; Rao, K.F.; Wang, Z.J. Occurrence of estrogenic effects in sewage and industrial wastewater in Beijing China. Environ. Pollut., 2007, 147: 331-336.
6. Jiang, Weiwei; Yan, Ye; Ma, Mei*; Wang, Donghong; Luo, Qian; Wang, Zijian. Assessment of source water contamination by estrogenic disrupting compounds in China. Journal of Environmental Sciences, 2012, 24(2) ,1–10.
7. Yan Ye, Jiang Weiwei, Li Na, Ma Mei*, Wang Donghong, Wang Zijian*, Rao Kaifeng. Assessing genotoxicity of 16 centralized source waters in China by SOS/umu test and micronucleus test and initial identification of the potential genotoxicants by GC/MS method and QSAR Toolbox 3.0. Mutation Research/Genetic Toxicology and Environmental Mutagenesis , 2014, 763, 36–43
8. Yan Ye, Jiang Weiwei, Li Na, Ma Mei*, Rao Kaifeng and Wang Zijian* Application of the SOS/umu test and highcontent in vitro micronucleus test to determine genotoxicity and cytotoxicity of nine benzothiazoles. Journal of Applied Toxicology, 2014, 34(12),1400-1408
9. Rong Yang, Na Li, Mei Ma, Zijian Wang, Combined effects of estrogenic chemicals with the same mode of action using an estrogen receptor binding bioassay, Environmental Toxicology and Pharmacology, 2014, 38(3),1382-1389
10. RongYang, Na Li, Kaifeng Rao, Mei Ma, ZijianWang, Combined action of estrogen receptor agonists and antagonists in two-hybridrecombinantyeast in vitro, Ecotoxicology and Environmental Safety , 2015, 111, 228–235
11. Na Li, Weiwei Jiang, Mei Ma*, Donghong Wang, Zijian Wang,Chlorination by-products of bisphenol A enhanced retinoid X receptordisrupting effects, Journal of Hazardous Materials, 2016, 320, 289-295
12. 3. Ying nan Han, Na Li, YoshimitsuOda, Mei Ma*, Kaifeng Rao, ZijianWang, Wei Jin, Gang Hong, Zhiguo Li, Yi Luo,Evaluation of genotoxic effects of surface waters
13. using a battery of Bioassays indicating different mode of action,Ecotoxicology and Environmental Safety, 2016, 133, 448–456
14. Ma Mei, Rao Kaifeng, Wang Zijian. 2007. Occurence of estrogenic effects in sewage and industrial wastewaters in Beijing, China. Environmental Pollution. 147: 331-336.
15. Kaifeng RAO, Na LI, Mei MA, Zijian WANG,2013. Determination of estrogens and estrogenic activities in water from three rivers in Tianjin, China. Journal of Environmental Sciences, 25(6): 1164–1171.
16. Xiaowei Jin, Yeyao Wang, Wei Jin; Kaifeng Rao, John Giesy; Henner Hollert, Kristine Richardson, Zijian Wang. 2014. Ecological risk of nonylphenol in China surface waters based on reproductive fitness. Environmental Science & Technology. 48(2): 1256-1262.
17. Chunmei Li, Donghong Wang*, Na Li , Qian Luo , Xiong Xu , Zijian Wang*,Identifying unknown by-products in drinking water using comprehensive two-dimensional gas chromatographye quadrupole mass spectrometry and in silico toxicity assessment,Chemosphere,2016,163:535-543
18. Qingwei Bu,Qian Luo,Donghong Wang*,Kaifeng Rao,Zijian Wang,Gang Yu,Screening for over 1000 organic micropollutants in surface water and sediments in the Liaohe River watershed,Chemosphere,2015,138:519-525
19. Bu, Qingwei,Wang, Donghong*,Liu, Xin,Wang, Zijian,A high throughout semi-quantification method for screening organic contaminants in river sediments,Journal of Environmental Management,2014,143:135-139
20. Bu, Qingwei,Wang, Donghong*,Wang, Zijian,Gu, Junnong,Identificat ion and ranking of the risky organic contaminants in the source water of the Danjiangkou reservoir,Frontiers of Environmental Science & Engineering,2014,8(1):42-53
21. Zhong, Wenjue,Wang, Donghong*,Xu, Xiaowei,Phenol removal efficiencies of sewage treatment processes and ecological risks associated with phenols in effluents,Journal of Hazardous Materials,2012,217–218:286-292
22. Qingwei Bu, Donghong Wang, Zijian Wang. Review of screening systems for prioritizing chemical substances. Critical Review in Environmental Science and Technology, 2013, 43:1011–1041,
23. Wenjue Zhong, Donghong Wang, Xiaowei Xu, Bingyi Wang, Qian Luo, S. Senthil Kumaran, Zijian Wang,A gas chromatography/mass spectrometry method for the simultaneous analysis of 50 phenols in wastewater using deconvolution technology. Chinese Science Bulletin, 2011, 56(3): 275-284
24. Zhong, W. J.; Wang, D. H.; Xu, X. W.; Luo, Q.; Wang, B. Y.; Shan, X. Q.; Wang, Z. J. Screening level risk assessment for phenols in surface water of the Taihu Lake. Chemosphere,2010, 80: 998-1005
25. Rui Hou, Yiping Xu*, Zijian Wang. Review of OPFRs in animals and humans: Absorption, bioaccumulation, metabolism, and internal exposure research. Chemosphere, 2016, 153(1): 78-90.
26. Chenglian Feng, Yiping Xu*, Jinmiao Zha, Jian Li, Fengchang Wu, Zijian Wang. Metabolic pathways of decabromodiphenyl ether (BDE209) in rainbow trout (Oncorhynchus mykiss) via intraperitoneal injection. Environmental Toxicology and Pharmacology, 2015, 39: 536-544.
27. Zijian Wang*, Shan Chen, Yiping Xu*, Jianfeng Tang. Aging effects on sorption-desorption behaviors of PAHs in different natural organic matters. Journal of Colloid and Interface Science, 2012, 382: 117-122.
28. Jianfeng Tang, Shan Chen, Yiping Xu, Wenjue Zhong, Mei Ma, Zijian Wang*. Calibration and field performance of triolein embedded acetate membranes for passive sampling persistent organic pollutants in water. Environmental Pollution, 2012, 164: 158-163.
29. Chenglian Feng, Yiping Xu, Gaofeng Zhao, Jinmiao Zha, Fengchang Wu, Zijian Wang*. Relationship between BDE 209 metabolites and thyroid hormone levels in rainbow trout (Oncorhynchus mykiss). Aquatic Toxicology, 2012, 122: 28-35.
30. Yiping Xu, Jay Gan*, Zijian Wang, Frank Spurlock. Effect of Aging on Desorption Kinetics of Sediment-Associated Pyrethroids. Environmental Toxicology and Chemistry, 2008, 27: 1293-1301.
31. Yiping Xu, Frank Spurlock*, Zijian Wang, Jay Gan. Comparison of Five Methods for Measuring Sediment Toxicity of Hydrophobic Contaminants. Environmental Science & Technology, 2007, 41: 8394-8399.
32. 高小中, 许宜平*, 王子健. 有机磷酸酯阻燃剂的环境暴露与迁移转化研究进展. 生态毒理学报, 2015, 10(2): 56-68.
33. 周东星, 高小中, 许宜平*, 王子健. 有机化合物生物富集的度量与评价方法进展. 环境化学, 2014, 33(2): 175-185.