张昱，博士，博士生导师，研究员，中国科学院大学岗位教授，现任环境水质学国家重点实验室副主任。曾先后在日本大阪大学、日本产业技术综合研究所（JSPS博士后）、美国俄克拉荷马大学开展合作研究。长期从事水质生物转化和调控技术研究及教学工作，近年来重点开展环境中抗生素抗性基因的传播与阻断、微量有害污染物转化与控制、废水/废弃物无害化与资源化技术等研究，成果应用于行业工程示范和环境管理。发表第一或通讯作者论文110余篇，SCI他引4000余次，获授权发明专利30余项，主持和参与编制国家和行业标准四项。获国家自然科学二等奖、国家科技进步二等奖等国家和省部级奖励多项。任中国生态学学会理事，中国城镇供水排水协会工程教育专委会委员，中国制药企业管理协会特聘EHS技术专家、国家环境保护抗生素菌渣无害化和资源化工程技术中心技术专家，入选世界卫生组织（WHO）抗微生物药物耐药性战略和技术咨询专家组，多次受邀参与WHO环境耐药性领域全球专家咨询会议，作为领域责任专家之一编制WHO/FAO/OiE于2020年联合发布的《关于防止感染和减少抗生素耐药性传播的水、环境、个人卫生和废水管理技术导则》。
1.国家自然科学基金面上项目：新型四环素类药物替加环素的环境细菌耐药特征及其产生机制研究，2021-2024
2.国家自然科学基金中英合作项目子课题：肠杆菌科细菌广泛耐药株/耐药基因在动物相关环境的传播与消减，2019-2022
3.中科院科技服务网络计划项目：制药废水的强化水解预处理技术工程化示范，2019
4.制药行业技术服务和转化：抗生素发酵菌渣无害化处理与资源化利用技术研发，2019-2021
5.水专项子课题：城市污水难去除及新兴微量污染物特征及去除途径研究，2017-2021
6.国家自然科学基金面上项目，抗生素废水处理剩余污泥中抗药基因在环境中的水平转移分子机制及调控原理研究，2013-2016
7.科技部国际合作子课题：水体中抗生素抗药菌和抗药基因的高效控制技术研究，2013-2016
8.中科院-日本学术振兴会国际合作课题，强化厌氧组合新工艺处理抗生素废水，2013-2015
9.水专项子课题：微量有害污染物在城市污水处理过程中的迁移转化规律研究，2012-2016
10.国家自然科学基金面上项目，抗生素残留效价在废水生物处理系统中的微生物生态效应与调控原理研究，2012-2015
11.国家自然科学基金面上项目，抗生素高胁迫条件下抗药基因的形成、传播和控制研究，2009-2011
12.水专项课题，城市污水再生利用及水质安全保障技术开发与工程示范，2008-2012
13.863探索课题：复合包覆型铝基稀土氧化物高效除氟剂开发及应用研究，2007-2010
14.国家自然科学基金面上项目，基于降解基因信息的壬基酚聚氧乙烯醚降解机制研究，2006-2008
15.日本学术振兴会(JSPS)博士后特別研究员奖励项目：Microbial ecology and resource of pollutants catabolizing microorganisms in aquatic environment，2005-2007
16.863青年课题，用于垃圾渗滤液中高氨氮去除的循环式MAP工艺研究，2004-2006
17.国家自然科学基金青年项目，金属氧化物配位羟基对水体有害阴离子的作用机制研究，2003-2005
1.国家自然科学二等奖，2017
2.国家科学技术进步二等奖，2006
3.华夏建设科学技术奖一等奖，2020
4.华夏建设科学技术奖二等奖，2015
5.中国石油和化学工业联合会技术发明奖二等奖，2016
6.中国科学院科技促进发展奖优秀成果奖二等奖，2015
7.安恒水处理化学青年成就奖，中国化学会水处理化学专委会，2012
8.IWA PIA (East Asia/Applied Research)（国际水协会东亚区应用研究奖），2010
9.北京市科技新星，2008
1.Tiantian Tian, Wei Qiao, Ziming Han, Xianghua Wen, Min Yang, Yu Zhang*. Effect of temperature on the persistence of fecal bacteria in ambient anaerobic digestion systems treating swine manure. Science of the Total Environment, 2021, 791: 148302.
2.Yanhong Shi, Zhe Tian, Michael R. Gillings, Yu Zhang*, Hong Zhang, Jiaoqi Huyan, Min Yang*. Novel Transposon Tn6433 Variants Accelerate the Dissemination of tet(E) in Aeromonas in an Aerobic Biofilm Reactor under Oxytetracycline Stresses. Environmental Science & Technology, 2020, 54: 6781-6791.
3.Ziming Han, Yu Zhang*, Wei An, Junying Lu, Jianying Hu, Min Yang*. Antibiotic resistomes in drinking water sources across a large geographical scale: Multiple drivers and co-occurrence with opportunistic bacterial pathogens. Water Research, 2020, 183: 116088.
4.Ziming Han, Wei An, Min Yang*, Yu Zhang*. Assessing the impact of source water on tap water bacterial communities in 46 drinking water supply systems in China. Water Research, 2020, 172: 115469.
5.Guangxi Sun, Yu Zhang*, Yingxin Gao, Xiaogang Han, Min Yang*. Removal of hard COD from biological effluent of coking wastewater using synchronized oxidation-adsorption technology: Performance, mechanism, and full-scale application. Water Research, 2020, 173: 115517.
6.Mei Tang, Yong Gu, Dongbin Wei, Zhe Tian, Ye Tian, Min Yang, Yu Zhang*. Enhanced hydrolysis of fermentative antibiotics in production wastewater: Hydrolysis potential prediction and engineering application. Chemical Engineering Journal, 2020, 391: 123626.
7.Jiaoqi Huyan, Zhe Tian, Yu Zhang*, Hong Zhang, Yanhong Shi, Michael R. Gillings, Min Yang*. Dynamics of class 1 integrons in aerobic biofilm reactors spiked with antibiotics. Environment International, 2020, 140: 105816.
8.Wanlin Zheng, Jiaoqi Huyan, Zhe Tian, Yu Zhang*, Xianghua Wen*. Clinical class 1 integron-integrase gene – A promising indicator to monitor the abundance and elimination of antibiotic resistance genes in an urban wastewater treatment plant. Environment International, 2020, 135: 105372.
9.Xiao Luan, Hong Zhang, Zhe Tian, Min Yang, Xianghua Wen, Yu Zhang*. Microbial community functional structure in an aerobic biofilm reactor: Impact of streptomycin and recovery. Chemosphere, 2020, 255: 127032.
10.Xiao-Xiao Yang, Tian-Tian Tian, Wei Qiao, Zhe Tian, Min Yang, Yu Zhang*, Jiu-Yi Li*. Prevalence and characterization of oxazolidinone and phenicol cross-resistance gene optrA in enterococci obtained from anaerobic digestion systems treating swine manure. Environmental Pollution, 2020, 267: 115540.
11.Mei Tang, Fan Li, Min Yang, Yu Zhang∗. Degradation of kanamycin from production wastewater with high-concentration organic matrices by hydrothermal treatment. Journal of Environmental Sciences, 2020, 97: 11-18. (封面文章)
12.Mei Tang, Xiaomin Dou, Zhe Tian, Min Yang, Yu Zhang*. Enhanced hydrolysis of streptomycin from production wastewater using CaO/MgO solid base catalysts. Chemical Engineering Journal, 2019, 355: 586-593.
13.Hiroyuki Kusada#, Yu Zhang#, Hideyuki Tamaki, Nobutada Kimura, Yoichi Kamagata*. Novel N-acylhomoserine lactone-degrading bacteria isolated from penicillin-contaminated environments and their quorum-quenching activities. Frontiers in Microbiology, 2019, 10: 1-9.
14.Zhe Tian, Ruyin Liu, Hong Zhang, Min Yang*, Yu Zhang*. Developmental dynamics of antibiotic resistome in aerobic biofilm microbiota treating wastewater under stepwise increasing tigecycline concentrations. Environment International, 2019, 131: 105008.
15.Hongrui Chen, Hui Peng, Min Yang, Jianying Hu, Yu Zhang*. Detection, Occurrence, and Fate of Fluorotelomer Alcohols in Municipal Wastewater Treatment Plants. Environmental Science & Technology, 2017, 51(16): 8953-8961.
16.Dev Raj Joshi, Yu Zhang*, Yingxin Gao, Yuan Liu, Min Yang. Biotransformation of nitrogen- and sulfur-containing pollutants during coking wastewater treatment: Correspondence of performance to microbial community functional structure. Water Research, 2017, 121: 338-348.
17.Qizhen Yi, Yu Zhang*, Yingxin Gao*, Zhe Tian, Min Yang. Anaerobic Treatment of Antibiotic Production Wastewater Pretreated with Enhanced Hydrolysis: Simultaneous Reduction of COD and ARGs. Water Research, 2017, 110: 211-217.
18.Zhe Tian, Yu Zhang*, Bo Yu, Min Yang. Changes of resistome, mobilome and potential hosts of antibiotic resistance genes during the transformation of anaerobic digestion from mesophilic to thermophilic. Water Research, 2016, 98: 261-269.
19.Qizhen Yi, Yingxin Gao, Hong Zhang, Haifeng Zhang, Yu Zhang*, Min Yang. Establishment of a pretreatment method for tetracycline production wastewater using enhanced hydrolysis. Chemical Engineering Journal, 2016, 300: 139-145.
20.Yu Zhang*, Zhe Tian, Miaomiao Liu, Zhou Jason Shi, Lauren Hale, Jizhong Zhou, Min Yang*. High Concentrations of the Antibiotic Spiramycin in Wastewater Lead to High Abundance of Ammonia-Oxidizing Archaea in Nitrifying Populations. Environmental Science and Technology, 2015, 49: 9124-9132.
21.Yu Zhang, Zhimin Chen, Wei An, Shumin Xiao, Hongying Yuan, Dongqing Zhang, Min Yang*. Risk assessment of Giardia from a full scale MBR sewage treatment plant caused by membrane integrity failure. Journal of Environmental Sciences, 2015, 30: 252-258. (封面文章)
22.Zhe Tian, Yu Zhang*, Yuyou Li, Yongzhi Chi, Min Yang. Rapid establishment of thermophilic anaerobic microbial community during the one-step startup of thermophilic anaerobic digestion from a mesophilic digester. Water Research, 2015, 69: 9-19.
23.Hong Zhang, Yu Zhang*, Min Yang. Miaomiao Liu. Evaluation of residual antibacterial potency in antibiotic production wastewater using a real-time quantitative method. Environmental Science Processes & Impacts, 2015, 17: 1923-1929.
24.Yu Zhang, Xin Gu, Jing Zhang, Min Yang*. Degradation pathways of low-ethoxylated nonylphenols by isolated bacteria using an improved method. Environmental Science and Pollution Research, 2014, 21: 9468-9476.
25.Miaomiao Liu, Ran Ding, Yu Zhang*, Yingxin Gao, Zhe Tian, Tong Zhang, Min Yang. Abundance and distribution of Macrolide-Lincosamide-Streptogramin resistance genes in an anaerobic-aerobic system treating spiramycin production wastewater. Water Research, 2014, 63: 33-41.
26.Zhiming Yan, Yu Zhang*, Hongying Yuan, Zhe Tian, Min Yang*. Fish larval deformity caused by aldehydes and unknown byproducts in ozonated effluents from municipal wastewater treatment systems. Water Research, 2014, 66: 423-429.
27.Yu Zhang, Jianping Xie, Miaomiao Liu, Zhe Tian, Zhili He, Joy D. van Nostrand, LirenRen, Jizhong Zhou, Min Yang*. Microbial community functional structure in response to antibiotics in pharmaceutical wastewater treatment systems. Water Research, 2013, 47: 6298-6308.
28.Xiaomei Wu, Yu Zhang*, Xiaomin Dou, Bei Zhao, Min Yang. Fluoride adsorption on an Fe–Al–Ce trimetal hydrous oxide: Characterization of adsorption sites and adsorbed fluorine complex species. Chemical Engineering Journal, 2013, 223: 364-370.
29.Yu Zhang, Min Yang*, Miaomiao Liu, Dong Li, Liren Ren. Antibiotic pollution from Chinese Drug manufacturing-antibiotic resistance. Toxicology letters, 2012, 211(S): S16.
30.Bei Zhao, Yu Zhang*, Xiaomin Dou, Xiaomei Wu, Min Yang. Granulation of Fe-Al-Ce trimetal hydroxide as a fluoride adsorbent using extrusion method. Chemical Engineering Journal, 2012, 185-186: 211-218.
31.Yu Zhang, Dongbin Wei, Rongde Huang, Min Yang*, Shujun Zhang, Xiaomin Dou, Dongsheng Wang, Vimonses Vipasiri. Binding mechanisms and QSAR modeling of aromatic pollutant biosorption on Penicillium oxalicum biomass. Chemical Engineering Journal, 2011, 166: 624-630.
32.Yu Zhang, Xiaomin Dou, Bei Zhao, Min Yang*, Tomoo Takayama, Shigeru Kato. Removal of arsenic by a granular Fe-Ce oxide adsorbent: Fabrication conditions and performance. Chemical Engineering Journal, 2010, 162: 164-170.
33.Xin Gu, Yu Zhang*, Jing Zhang, Min Yang*, Hideyuki Tamaki, Yoichi Kamagata, Dong Li. Isolation of phylogenetically diverse nonylphenol ethoxylate-degrading bacteria and characterization of their corresponding biotransformation pathways. Chemosphere, 2010, 80: 216-222.
34.Yu Zhang, Kazunari Sei, Tadashi Toyoma, Michihiko Ike, Jing Zhang, Min Yang*, Yoichi Kamagata. Change of catabolic genes and microbial community structures during biodegradation of nonylphenol ethoxylates and nonylphenol in natural water microcosms. Biochemical Engineering Journal, 2008, 39: 288-296.
35.Yu Zhang*, Xiaomin Dou, Jian Liu, Min Yang*, Liping Zhang, Y. Kamagata. Decolorization of Reactive Brilliant Red X-3B by Heterogeneous Photo-Fenton Reaction using an Fe-Ce bimetal catalyst. Catalyst Today, 2007, 126: 387-393.
36.Yu Zhang, Min Yang*, Xiaomin Dou, Hong He, Dongsheng Wang. Arsenate Adsorption on an Fe-Ce Bimetal Oxide Adsorbent: Role of Surface Properties. Environmental Science & Technology, 2005, 39: 7246-7253.
37.Yu Zhang, Min Yang*, Xia Huang. Arsenic removal with a Ce-doped iron oxide adsorbent. Chemosphere, 2003, 51: 945-952.
1. 杨敏，张昱，高迎新等，工业废水处理与资源化技术原理及应用，化学工业出版社，2019
2. Yu Zhang et al., CHAPTER 6, Milestones in Water Reuse: The Best Success Stories, IWA Publishing, Publication Date:15/01/2013